Terpenoid cyclases catalyze the most complex reactions in biology, in that more than half of the substrate carbon atoms often undergo changes in bonding during the course of a multistep cyclization ...

Using a clever chemogenetic suppression analysis, the authors provide compelling evidence that an RNA enzyme uses general acid catalysis. Their approach, which merges chemical substitution with enzyme ...

(Nanowerk News) Enzymes are catalysts that speed up chemical reactions in living organisms and control many cellular biological processes by converting a molecule, or substrate, into a product used by ...

Shedding insights into the acid-base properties at the atomic level is crucial for heterogeneous catalysis. How to detect and identify the geometric structure, exact position and the acid-base ...

Diacylglycerol O-acyltransferase 1 (DGAT1), the rate-limiting enzyme in triacylglycerol (TAG) biosynthesis, is a crucial ...

University of Groningen chemists have created a new enzyme with an unnatural amino acid as its active centre. They made the enzyme by modifying an antibiotic binding protein which normally acts as a ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, No. 15 (Jul. 21, 1998), pp. 8449-8454 (6 pages) Arginine kinase belongs to the family of enzymes, including ...

Scientists at the University of Groningen turned a non-enzymatic protein into a new, artificial enzyme by adding two abiological catalytic components: an unnatural amino acid and a catalytic copper ...

A new study published in the journal Nature Catalysis on February 10, 2020, reports the creation of a new artificial enzyme from two components, both non-biological in origin. This event marks the ...

The Post group has worked to understand the basis of the catalytic power of enzymes using information from crystallography, kinetics, and a description of conformational distributions from molecular ...

A research team led by the University of California, Irvine has engineered an efficient new enzyme that can produce a synthetic genetic material called threose nucleic acid. The ability to synthesize ...

A recent book shows the links between synthesis, catalysis, and environmental protection. Active pharmaceutical ingredients (APIs) are traditionally chemical moieties synthesized according to the ...