Following an injury, such as a traumatic crush injury, the peripheral nervous system is itself often able to effectively regenerate. This regeneration capacity is mainly attributable to the Schwann ...

Newborn nerve cells must squeeze through crowded, narrow spaces—through dense tissue, past other cells, and between fibers—to reach the areas where they form neural circuits in the brain cortex. In a ...

As muscles age, their cells lose the ability to regenerate and heal after injury. Cornell Engineering researchers have created the most comprehensive portrait to date of how that change, in mice, ...

Migrating newborn neurons suffer routine double-strand DNA breaks from physical stress during brain development.

Bone fracture healing is a dynamic process that relies on coordinated cellular interactions for effective tissue regeneration. We employ optimized spatial transcriptomics to delineate the locations ...

Lysosomes are membrane-bound organelles that play a crucial role in cellular homeostasis by maintaining nutrient recycling, degrading cellular waste, and regulating various cellular processes. 1 They ...

Amyotrophic lateral sclerosis (ALS) is a relatively rare but very serious disease of the nervous system. A cure is not yet possible. ALS slowly destroys the motor neurons in the brain and spinal cord ...

Researchers at Rice University developed a cytokine factory patch that continuously releases healing proteins into wounds, accelerating tissue repair in mice and pigs while activating key regeneration ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Ultraviolet (UV) radiation is known to cause DNA damage, and while that damage may accumulate and eventually lead to diseases like skin cancer, cells also have repair mechanisms that can fix ...

In the evolutionary history of life, the ability of a cell to separate its inner world from the external environment was an important turning point. The so-called plasma membrane lets cells control ...