The Bills have the Chiefs' number in regular-season play. They are 5-1 against Kansas City in regular-season meetings since 2017 and won each of the last four matchups. It is when the stakes are at their highest that the Chiefs take control. They won each of the four playoff showdowns since Mahomes and Allen joined their respective teams.

As for the Chiefs’ run game, it’s been by committee. Isiah Pacheco, Kareem Hunt and Brashard Smith have all seen action. Pacheco has led the way this season with 329 yards but suffered a knee injury in Week 8 against the Washington Commanders. He’s now considered week-to-week and ruled out for Sunday’s game against the Bills.