At the start of each ubiquitin-like protein (UBL) cascade is an E1 enzyme, which activates the UBL and then directs the UBL to downstream pathways. UBL proteins and E1 (or activating) enzymes have ...
In all organisms, innate immune pathways sense infection and rapidly activate potent immune responses while avoiding inappropriate activation (autoimmunity). In humans, the innate immune receptor ...
Yan Geng, Qunyan Yu, Wendy Whoriskey, Fred Dick, Kenneth Y. Tsai, Heide L. Ford, Debajit K. Biswas, Arthur B. Pardee, Bruno Amati, Tyler Jacks, Andrea Richardson, Nicholas Dyson, Piotr Sicinski ...
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