Assembly of HIV-1, which causes AIDS, takes place on the inner plasma membrane leaflet of infected cells, a geometric building process that creates hexamers out of trimers of the viral Gag protein, as ...

Jamil Saad, Ph.D. Jamil Saad, Ph.D., professor in the Department of Microbiology, is the latest winner of the Heersink School of Medicine’s Featured Discovery. This initiative celebrates important ...

Since HIV’s discovery in the 1980s, scientists have come a long way in understanding the different steps required for its assembly and maturation. Researchers knew, for instance, that HIV wraps its ...

Peering into the fascinating world of HIV biology, researchers at the Gladstone Institute of Virology and Immunology have found that an HIV gene called Vpr causes the membrane surrounding the ...

The ideal HIV vaccine would elicit humoral responses effective against a broad spectrum of primary HIV strains but immunogens capable of generating such antibodies in humans have been difficult to ...

The enormous genetic diversity between individual HIV-1 viruses presents a difficult hurdle for vaccine design, as the vaccine-elicited antibodies must neutralize a large range of HIV envelope (Env) ...