The term “protease inhibitor” refers to a class of medications rather than to a single medication. Specifically, they are antiviral drugs. But unlike the many, more common antiviral drugs that can be ...

Figure 1: Structural organization of Gag-Pol polyprotein in HIV-1. We speculated that the low catalytic activity of the native p6 pol-protease precursor that is observed preceding its maturation may ...

Protease inhibitors block a cellular enzyme crucial to creating structure of nucleus. Researchers have demonstrated that HIV protease inhibitors block a cellular enzyme important for generating the ...

No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2006 ASCO Annual Meeting. This abstract does not include a full text component.

A preliminary study to be presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Lisbon, Portugal (23-26 April), suggests that people living with HIV who ...

Lexington, MA -- Concert Pharmaceuticals, Inc. announced today that it has initiated a Phase 1b clinical study with CTP-518, its investigational oral HIV protease inhibitor for the treatment of HIV ...

Social media users have questioned why a treatment approved to treat COVID-19 contains an HIV protease inhibitor. It comes after the United States authorised Pfizer's antiviral Paxlovid as the first ...

Alpha macroglobulin (AM) protease inhibitors utilize a unique trapping mechanism that allows them to inhibit proteases of any catalytic class. The best-known AM protease inhibitor is A2M, a large ...