Myeloproliferative neoplasms (MPNs) are myeloid malignancies characterized by the expansion of a multipotent hematopoietic progenitor stem cell [1, 2]. Philadelphia-negative MPNs in the chronic phase ...
During each cell cycle, the process of DNA replication timing is tightly regulated to ensure the accurate duplication of the genome. The extent and significance of alterations in this process during ...