Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor immunity.

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in over 100 million infections and millions of deaths. Effective vaccines remain the best hope of ...

MHC-I presents viral antigens for CD8+ cytotoxic T lymphocyte (CTL) activation. Upon activation, these cells kill and eliminate virus-infected cells throughout the human body. Several viruses have ...

Cancer immunotherapy has transformed cancer treatment, yet many patients experience limited or short-lived responses due to immune evasion, tumor heterogeneity, and immune-related adverse events.

Neoantigen vaccines are at the forefront of cancer research, driving personalized immunotherapy and improving outcomes ...

The chicken major histocompatibility complex (MHC) represents a compact and evolutionarily distinct genomic region that plays a critical role in orchestrating adaptive immunity. Characterised by a ...

The adaptive immune system is an antigen-specific structure that discriminates non-self molecules through the recognition of peptide antigens using receptor interactions between T-cells and ...

“Allogeneic hematopoietic stem cell transplantation is a curative therapy for hematopoietic malignant and non-malignant disease. However, the immunological complication known as graft-versus-host ...

Peptides that bind major histocompatibility complex (MHC) class I molecules act as chemosensory signals in a region of the brain thought to be important in chemosensory communication, according to a ...