Molecular beacons are hybridization probes that can report the presence of complementary nucleic acid targets without having to separate probe–target hybrids from excess probes in hybridization assays ...

When one is detecting nucleic acids by hybridization, there are numerous situations in which it is not desirable to isolate probe-target complexes from the excess of probes that are used. Sanjay Tyagi ...

Molecular beacons, single-stranded oligonucleotides that have a fluorescent "reporter" group at one end and a fluorescence "quencher" at the other, do not suffer from these shortcomings. 1 When free ...

Adherent cells, the kind that form the architecture of all multi-cellular organisms, are mechanically engineered with precise forces that allow them to move around and stick to things. Proteins called ...

After the start of the SARS-C0V-2 pandemic, investigators from ResearchPath LLC and their collaborators at Rutgers University quickly dedicated resources to develop accurate and reliable COVID-19 ...

Premier Biosoft International has announced the release of version 5.10 of Beacon Designer with advanced support for multiplexing, crucial for diagnostic assay development. Beacon Designer is their ...

Scorpions ™ Primers integrate primer and probe into a single bifunctional molecule. Unlike dual-labeled probes and Molecular Beacons, Scorpions Primers combine primer and probe in one molecule, with ...