Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

New wearable device technology and research from the University of Wisconsin-Madison allows doctors to measure muscle-tendon forces in a non-invasive method. Even though today we can easily measure ...

Mechanical overload might be the most important principle in strength training. It involves loading the target muscle to the point of fatigue, and ultimately, mechanical failure. When the target ...

Combining lab-grown muscle tissue with a series of flexible mechanical joints has led to the development of an artificial hand that can grip and make gestures. The breakthrough shows the way forward ...

Accomplishing perhaps a world first, researchers at Columbia University and the UChicago-affiliated Marine Biological Laboratory have mapped the full-body muscular activity of an animal while it was ...

WASHINGTON-(Dec. 24, 2018)-Children with life-threatening respiratory failure who require mechanical ventilation in a pediatric intensive care unit commonly experience rapid muscle atrophy, according ...

Prions, mysterious shape-shifting proteins, can lead to brain disorders such as Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy, "mad cow disease" in cattle, yet they can also ...