ROS-producing enzymes guide plant cell division and tissue patterning, gene-editing study shows

Reactive oxygen species (ROS) produced naturally during cellular metabolism often cause oxidative damage to cells. However, ...
Nature

DNAJC5 facilitates the proliferation and migration of lung adenocarcinoma cells by augmenting EGFR trafficking

Lung cancer is one of the most prevalent malignancies worldwide, exhibiting high incidence and mortality rates, resulting in approximately 1.76 million deaths annually 1. Histopathologically, lung ...

CT researchers looked at how our skin rebuilds itself. What they found challenges assumptions.

A new study from Yale School of Medicine, published in the Journal of Cell Biology, challenges that assumption. When ...
Medical Xpress

Mitochondria support T-cells proliferation and memory formation

Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports ...
Nature

Myc-mediated epigenetic silencing of ACAP3 promotes lung adenocarcinoma proliferation via regulating EGFR dynamics

Despite significant advances in diagnosis and therapy, the prognosis of late-stage lung adenocarcinoma (LUAD) remains poor, underscoring the urgent need for effective biomarkers to enable early ...
EurekAlert!

Mitochondrial dynamics in normal and cancer cells (IMAGE)

Mitochondrial dynamics, governed by the interplay of fission and fusion proteins, are essential for maintaining cellular function and homeostasis. Fission facilitates glycolysis, mitophagy, apoptosis, ...