The orbitofrontal cortex (OFC), a subsection of the brain's frontal lobe, is known to play a part in value-based decision-making, the process of mentally weighing the outcome of different decisions ...

A team of researchers at Boston University has found that applying low-frequency electrical stimulation to the orbitofrontal cortex of obsessive-compulsive behavior patients proved to be effective in ...

New research published in JCCP Advances indicates that experiencing negative life events (NLE) during childhood is linked with a higher risk of developing symptoms of depression during young adulthood ...

In a recent study published in the journal JCPP Advances, a group of researchers investigated whether early negative life events (NLEs) predict depressive symptoms in young adulthood through ...

Humans and other animals gradually learn what sounds or other sensory cues in their surroundings are meaningful or potentially threatening. Via a process known as habituation, they gradually learn to ...

A new study links anxiety, the orbitofrontal cortex (OFC), and optimism, finding that healthy adults who have larger OFCs tend to be more optimistic and less anxious. The new analysis, reported in the ...

Depression imposes a major global socioeconomic burden, and current pharmacotherapies face several limitations, including slow efficacy, adverse effects, and non-response rates of up to 55%, ...

The human brain is remarkably adept at adjusting what we hear based on contexts, like our current environment or priorities, but it's still unknown how exactly the brain helps us detect, filter and ...

Summary: Researchers have identified the causal circuits of OCD for the first time. Rather than relying on traditional ...