During development, cells grow, expand, and migrate to generate tissues and organs in a highly controlled manner. Many intracellular pathways – series of signalling cascades within a cell – regulate ...

In a new study published in the New England Journal of Medicine, researchers led by Charis Eng, MD, PhD and Pier Paolo Pandolfi, MD, PhD, FRCP determined that mutations of the WWP1 gene may also drive ...

One of PTEN's roles in the body is as a tumor suppressor gene, which means that when it works correctly, PTEN helps suppress the growth of any cells trying to grow out of control and become tumors.

A study published in Science Advances reveals a novel strategy that allows tumors to evade the body's immune response critical for their elimination. Researchers at Baylor College of Medicine and ...