Disulfide bonds play a pivotal role in the folding and stability of many bacterial proteins, influencing not only their tertiary structure but also their biological activity. In bacteria, the ...
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Tiny protein pair discovery could reveal how the genetic code first began
Life runs on instructions you never see. Every cell reads DNA, turns that message into RNA, and then builds proteins that ...
Researchers have shown that harmful bonds between protein and DNA fuel immune attack in progeria. Pumping up a protein that cuts these bonds could prevent symptoms.
Proteins can form “catch-bonds” that tighten under force, much like a finger trap. Using artificial intelligence and molecular simulations, Auburn scientists uncovered how these bonds strengthen ...
AI analysis uncovers why certain protein interactions behave like a finger trap, gripping tighter the harder they’re pulled. Imagine tugging on a Chinese finger trap. The harder you pull, the tighter ...
The study results, published June 5 in The EMBO Journal, shed new light, researchers say, on the way the altered mitochondrial membranes found in people with metabolic diseases such as Barth syndrome, ...
The Flagship Pioneering spinout uses permanent bonds to target shallow pockets, drastically expanding the druggable universe for small molecules.
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