These systems can be tailored to enhance detection. The intersection of nanopore-based sensing and oligomer characterization requires many chemical insights, not only in understanding the biochemistry ...

To handle increasingly large protein databases, a new ultrafast, highly sensitive method — Dense Homolog Retriever (DHR) — detects remote homologs using dense retrieval and protein language models.

Protein complexes are important for the majority of vital processes in the cell and human body, such as producing energy, copying DNA and regulating the immune system. Composed of groups of connected ...

Since the 1950s, researchers have used flow cytometry to characterize in immune and other cell types by detecting proteins with antibodies that are linked to fluorescent probes and later also ...

By combining CRISPR knock-in with small peptide tags, researchers can study proteins in their native cellular context, ...

D&D‑seq uses base editing to record DNA–protein interactions in single cells, enabling multiomics mapping of transcription factor and other regulatory proteins.

Northwestern Medicine scientists have developed a new experimental method to analyze conformational fluctuations in protein domains on a uniquely large scale, which may improve data-driven modeling, ...

Researchers say they have used a high-sensitivity mass spectrometry technique to improve the accuracy of sandwich ELISA. The team, from biopharmaceutical company Regeneron, hopes their work will help ...

Researchers recently published findings that could lay the groundwork for applying quantum computing methods to protein structure prediction. Researchers from Cleveland Clinic and IBM recently ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...