Protein lactylation is an emerging field. To advance the exploration of its biological functions, here we develop a comprehensive workflow that integrates proteomics to identify lactylated sites, ...

Cells actively maintain complex lipidomes that encompass thousands of lipids; however, many of the roles of these lipids remain unexplored. Specific interactions between lipids and membrane proteins ...

Scientists from the National University of Singapore (NUS) have developed a biochemical technique that captures fleeting "handshakes" between newly made proteins and the cellular helpers. These short ...

T cells are crucial components of our immune system, serving as critical protectors against infection and disease. But there are limits to their defensive capabilities. T cells are not inexhaustible ...

Origami masters turn simple sheets of paper into ornate sculptures. In the origami of life, our cells must fold proteins into ...

A project at Aston University to extract proteins from cell membranes for better drug discovery and testing has won a Biotechnology and Biological Sciences Research Council (BBSRC) Network grant of ...

A new method developed by researchers at the Nuffield Department of Medicine, University of Oxford, could soon unlock the vast repository of biological information held in the proteins of ancient soft ...

Tissue processing advance can label proteins at the level of individual cells across whole, intact rodent brains and other large samples just as fast and uniformly as in dissociated single cells. A ...