After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, ...

An investigation by researchers from Case Western Reserve University School of Medicine in the US has filled in a missing link between the toxic build-up of proteins in the neurodegenerative condition ...

In 1817, a British physician named James Parkinson published An Essay on the Shaking Palsy, describing for the first time cases of a neurodegenerative disorder now known as Parkinson’s disease. Today, ...

How One Tiny Cellular Structure Holds the Key to Better Health & Longevity — and How You Can Harness It ...

For decades, scientists have known that a misbehaving protein sits at the heart of Parkinson’s disease, yet the precise chain ...

In Parkinson’s disease (PD), damaged mitochondria build up in the dopaminergic system of the substantia nigra, partly due to impaired mitochondrial autophagy (mitophagy) and autophagosome accumulation ...

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have ...

Barth syndrome is a rare genetic disorder caused by mutations in the TAZ gene, which encodes an enzyme essential for remodeling cardiolipin, critical for mitochondrial function. A recent study ...

Patch-clamp recordings demonstrated that LHON neurons, which typically exhibit impaired sodium and potassium currents, showed restored electrophysiological function after co-culture with MSCs.