After a much-needed day off, the St. Louis Cardinals open another home series Friday night versus the Cincinnati Reds. Kyle Leahy will make the start for the Cardinals while the Reds are scheduled to send Brady Singer to the mound.

Cincinnati Reds (31-31, fifth in the NL Central) vs. St. Louis Cardinals (33-28, second in the NL Central) St. Louis; Saturday, 2:15 p.m. EDT PITCHING PROBABLES: Reds: Nick Lodolo (2-1, 5.20 ERA, 1.37 WHIP,

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Don't expect to see the St. Louis Cardinals swing some sort of blockbuster deal.

Let’s not be overdramatic since it’s only the end of May, but I believe this weekend’s St. Louis Cardinals versus Chicago Cubs clash at Busch Stadium is more important than we probably think all because of one word – trajectory.

This weekend’s series, which begins Friday, marks the first meeting between the Cubs and Cardinals this season in one of baseball’s most historic rivalries. Chicago won the 2025 season series 8-5 and leads the all-time series 1,281-1,226-19.

A new era of watching Cardinals baseball is here, and Cardinals.TV presented by bet365 has you covered all season long.

Author and historian Ed Wheatley joins Derrick Goold to discuss his new book about how 50 famous Rawlings gloves illustrate the game

The St. Louis Cardinals have a hurler that any team in baseball would be fortunate to have in closer Riley O'Brien. While O'Brien has been in the middle of a cold streak recently, he still has a 3.95 ERA and 15 saves in 27 outings so far this season.