The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, ...
New findings describe how the enzyme CST is recruited to the end of the telomere, where it maintains telomere length with the help of subtle chemical changes made to the protein POT1. The length of ...
Scientists have mapped out the molecular structure of a key part of our chromosomes called telomeres, which play a pivotal part in aging and cancer. Scientists from Nanyang Technological University, ...
As we age, our appearance changes, our hair turns gray and wrinkles appear. And we become more susceptible to disease. One reason for this is that our telomeres shorten. These are protective caps at ...
Longer leukocyte telomere length is associated with higher left ventricular mass (LVM) and larger global ventricular size, as well as better cardiac function and lower risk of heart failure (HF). The ...
Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres - regions of repetitive DNA sequences and a protein structure - protect the tips of chromosomes from damage. Every ...
Telomere shortening — a sign of cellular aging — is associated with multiple changes in the brain associated with dementia, whereas longer telomeres associate with better brain health and lower risk ...
CST (purple/lavender) bound to POT1 (red). Phosphorylation of the crimson-highlighted region in POT1 regulates the recruitment and activity of CST–Polα-primase at telomeres. The length of telomeres ...
Scientists from Nanyang Technological University, Singapore (NTU Singapore) have mapped out the molecular structure of a key part of our chromosomes called telomeres, which play a pivotal part in ...
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