A graph-based computational tool for detecting previously invisible genetic mutations has been developed. Researchers at the University of California, Los Angeles (UCLA; USA) and the University of ...

KRAS is the most frequently mutated oncogene across all human cancers. Although different KRAS mutations have long been thought to exert the same cancer-driving effects, a new study led by UT ...

This research provides a comprehensive analysis of deleterious mutations in pear (Pyrus spp.) during domestication, shedding light on their impact on agronomic traits. By resequencing 232 pear ...

Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...

How fast does the human genome change? Scientists have attempted to answer this question by studying mutation rates over several generations, and they found that some parts of the human genome tend to ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth. The study focused on CTNNB1, a gene that produces the protein β-catenin, ...