This image illustrates the typical steps in next-generation sequencing (excluding single-molecule sequencing methods). The process begins with isolating genomic DNA (a) and breaking it into short ...

In the United States, healthcare professionals classify a disease as rare if it affects fewer than 200,000 individuals. As of August 7, 2024, the U.S. population consists of just under 336.9 million ...

Nanopore sequencing offers comparable accuracy to short-read NGS for IGH clonotyping in CLL, with advantages in cost and laboratory footprint. The study confirms reliable somatic hypermutation status ...

Variant detection of multiple genes from a single tumor sample requires high-throughput molecular testing. To meet this demand, targeted next-generation sequencing (NGS) panels are useful in clinical ...

In this Teach Me in 10 episode, Dr. Christina Chang, Director of Assay Applications, Spatial Genomics R&D at Takara Bio USA, ...

NGS enables the in-depth analysis of the genome and the identification and investigation of disease-associated variants–especially when workflows include target enrichment, which focuses on specific ...

This application note highlights how capture-based NGS panels deliver high sensitivity and precision while reducing workflow duplication and bias.

For decades, formalin-fixing paraffin-embedding has been the preferred method for preserving biological samples for diagnostic research. Formalin is relatively inexpensive and can be used to preserve ...

Automated library preparation is critical for reducing errors, increasing repeatability, and reducing hands-on time, allowing researchers to generate sequence data from DNA more quickly. The CyBio ...

The last three years have been anything but static for next-generation sequencing (NGS) companies. Several competitors have launched new sequencing technologies that have taken direct, and often ...

Circulogene today announced the national launch of OncoGenDx, an innovative tissue-based comprehensive genomic profiling (CGP ...