Cryo-EM reveals how Wnt, a key signal molecule for human development and cancer, is modified by an enzyme named PORCN. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news ...

The resulting images became the first known structure of a complete aGPCR. The cryo-EM images showed that the GAIN domain of the receptor assumed several different positions in relation to the ...

This “exposure” yields many 2-D images of the molecules at different angles, which algorithms then merge into one 3-D model. At first cryo-EM rendered molecules as vague lumps, so some ...

"The effort of producing high-resolution cryo-EM images is wasted if they are compromised by poor sample preparation," Usukura says. He advises that a good sample for cryo-EM is, most importantly ...

Moreover, data collection at low temperature reduces sample damage by the electron beam, improving the resolution of the EM images. This paper thus marks the early development of cryo-EM.

The model uses data from pictures of frozen molecules captured by powerful microscopes, or cryo-electron microscopy (cryo-EM) ...

The Cryo-Electron Microscope (cryo-EM) market has witnessed significant advancements in recent years, driven by the increasing demand for high-resolution imaging techniques across various industries.

Cryo-EM & Cryo-ET Meeting at NYU Langone! Share unpublished work, discuss breakthroughs, and tackle challenges. June 25.

For each structural strain of tau fibrils, they identified amino acids without which the strain cannot form its signature ...