The translocator protein (TSPO) is expressed at low levels in the healthy human brain and is markedly upregulated in response to brain injury and inflammation. This increase in TSPO expression is ...
Fibroblast activation protein (FAP) has become an attractive target for diagnosis and therapy, and a series of FAP inhibitor (FAPI)–based radiotracers has been developed and had excellent performance ...
The charity Children’s Cancer Research Fund (https://www.childrenscancerresearchfund.co.uk/) convened a symposium in Manchester, U.K., in September 2024. Twenty-one invited speakers included pediatric ...
Journal of Nuclear Medicine September 2026, jnumed.126.272814; DOI: https://doi.org/10.2967/jnumed.126.272814 ...
Medically intractable complex partial seizures can be cured or improved using surgery, but accurate preoperative localization of the seizure focus is essential for complete seizure control.
Radioimmunotherapy and nuclear imaging (immuno-PET/SPECT) of cancer with radiometal-labeled antibody fragments or peptides is hampered by low tumor-to-kidney ratios because of high renal radiometal ...
The recently released Biograph mMR is the first commercially available integrated whole-body PET/MR scanner. There are considerable advantages to integrating both modalities in a single scanner that ...
PET/CT imaging of cancer with combined PET and CT scanners has become a standard component of diagnosis and staging in oncology (1,2). The glucose analog 18 F-FDG has been shown to concentrate in ...
Receptors for regulatory peptides are overexpressed in a variety of human cancers. They represent the molecular basis for in vivo imaging with radiolabeled peptide probes. Somatostatin-derived tracers ...
TheraPb Phase 1b: First-in-Human Dose-Escalation and Optimization Study of 212 Pb-ADVC001 in PSMA-Positive Metastatic Androgen Pathway Modulation–Resistant Prostate Cancer ...
Journal of Nuclear Medicine May 2024, jnumed.124.267417; DOI: https://doi.org/10.2967/jnumed.124.267417 ...
This review explores the role of PET in imaging immune activation, particularly in oncology. 18 F-FDG is widely used for assessing treatment response to immunotherapies and can demonstrate unique ...
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