Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The molecular mechanisms controlling the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Auxin dictates root architecture via the Auxin ...

Contact of developing sensory organs with the external environment is established via the formation of openings in the skin. During eye development, eyelids first grow, fuse and finally reopen, thus ...

Apoptosis and inflammation generally exert opposite effects on tumorigenesis: apoptosis serves as a barrier to tumour initiation, whereas inflammation promotes tumorigenesis. Although both events are ...

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This month's cover highlights the article Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation by A.-D. Brunner, M. Mann and colleagues. A new ultra-high ...

Precursor protein targeting toward organellar surfaces is assisted by different cytosolic chaperones. We demonstrate that the chloroplast protein translocon subunit Toc64 is the docking site for Hsp90 ...

Cell membranes are fascinating supramolecular aggregates that not only form a barrier between compartments but also harbor many chemical reactions essential to the existence and functioning of a cell.

Eukaryotic up‐frameshift 1 (UPF1) is a nucleic acid‐dependent ATPase and 5′‐to‐3′ helicase, best characterized for its roles in cytoplasmic RNA quality control. We previously demonstrated that human ...

The formation of cell type‐specific complexes is crucial for the development of complex organisms. Unique combinations of LIM‐homeodomain (LIM‐HD) proteins are thought to form a transcriptional ‘LIM ...

Intercellular adhesion molecule‐1 (ICAM‐1) is a crucial receptor in the cell–cell interaction, a process central to the reaction to all forms of injury. Its expression is upregulated in response to a ...