With that, here are Bills Wire’s five takeaways from Week 16: The Bills got off to a shocking start against the Patriots. As ...

Follow along with score and in-game updates as the Bills host the Patriots on Sunday afternoon at Highmark Stadium.

Cam Lewis’ first career interception with the Buffalo Bills on Sunday may come with a steep cost.

Buffalo still has a chance to secure home-field advantage throughout the AFC playoffs, but it would need to keeping winning, and get help elsewhere.

When the Bills won the toss and deferred, the Lions couldn’t afford to play into their hands. This game was about points, ...