Single-celled organisms have more complex DNA epigenetic code than multicellular life, researchers discover

Multicellular organisms (animals, plants, humans) all have the ability to methylate the cytosine base in their DNA. This ...
EMBO Press

NANOG governs cell metabolism and redox homeostasis in human naïve embryonic stem cells

NANOG has multifaceted roles in naïve hESCs, orchestrating transcriptional, metabolic, and epigenetic signatures in naïve hESCs, and governing acetyl-CoA synthesis, bivalent metabolism, and redox ...
Carnegie Science

Chemical evidence of ancient life detected in 3.3-billion-year-old rocks

Washington, DC— Pairing cutting-edge chemistry with artificial intelligence, a multidisciplinary team of scientists found ...

AI Uncovers Hidden Traces of Life in 3.3 Billion-Year-Old Rocks

AI-powered chemical analysis uncovered faint biological fingerprints in some of Earth’s oldest rocks, pushing back the origins of oxygen-producing life.
eLife

Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein

The hold-and-release regulation of zinc by GIF/MT-3 is mediated by sulfane sulfur through a redox-dependent switching mechanism.