The FDA has begun soliciting feedback to inform the next version of the Prescription Drug User Fee Act. User fees remain ...

A 28-year-old woman was admitted to the hospital because of severe hypoxemia and right heart failure that had been caused by rapidly progressive pulmonary hypertension. A diagnosis was made.

MASLD has become the most common chronic liver disease worldwide. The authors review the features of the disease as well as pharmacotherapies targeting the associated liver and cardiovascular ...

A small-molecule drug proves its mettle in the treatment of spinal muscular atrophy, a disease amenable to intervention at the pre-mRNA level.

A man from rural India presented with redness and blurry vision in one eye. Examination was notable for panuveitis and a live worm in the posterior segment; the worm was removed in a pars plana vit ...

Though infant mortality has continuously been targeted by health policy agendas, policies tend to place it in an individualistic and narrow frame, failing to consider and address its structural ...

The rising tide of chronic kidney disease among patients with type 2 diabetes continues to challenge clinicians and health systems worldwide.1 Advances have been made in the management of chronic k ...

To prevent the spread of inaccurate information, academic and health care institutions will need to equip scientists and clinicians to engage effectively on nontraditional media platforms.

Audio Interview from the New England Journal of Medicine — Interview with Arthur Robin Williams on alcohol consumption in the United States and the effects of alcohol taxes.

The author describes the implementation of a clinical-care program involving pronuclear transfer to minimize the transmission of mitochondrial disease. He also describes the long pathway leading to ...

In 15 patients with primary aldosteronism, baxdrostat (a second-generation, nonimidazole aldosterone synthase inhibitor) resolved or reduced the severity of hypertension, excessive aldosterone ...

During 2018–2024, the percentage of N. gonorrhoeae isolates carrying tetM, which confers tetracycline resistance, increased from less than 10% to more than 30% across the United States.