The authors’ approach is deceptively simple: take an aldehyde dehydrogenase enzyme, which naturally converts aldehydes to acids, and get it to react with an amine instead of water. But actually making ...

(RTTNews) - Newron Pharmaceuticals reported the publication of preclinical research in the peer-reviewed journal Neuropsychopharmacology on the mechanism and site of action of evenamide as a potential ...

Mutation of DJ-1 is implicated in hereditary Parkinson’s disease. However, the exact molecular mechanism of its pathophysiological role was unknown. Researchers from Japan used molecular simulations ...

Extending or trimming the length of a drug molecule’s carbon backbone by just a couple of atoms can significantly alter its activity, even if nothing else in the structure changes. So reactions that ...

Mycotoxins are secondary metabolites produced during the growth, storage, and transportation of crops contaminated by fungi and are physiologically toxic to humans and animals. Aflatoxin, zearalenone, ...

Microtubules (MTs) are large and dynamic components of the eukaryotic cytoskeleton with the ability to stochastically convert from a polymerizing to a depolymerizing state and vice versa.

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Hydrolysis of N₂O₅ under tropospheric conditions plays a critical role in assessing the fate of O₃, OH, and NOₓ in the atmosphere. However, its removal mechanism has not been fully understood, and ...