Researchers at The Institute of Cancer Research, London, have uncovered how the DNA repair enzyme XPF-ERCC1 is recruited to sites of damage and activated inside cells, resolving a long-standing ...
In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would ...
DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...
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New research reveals RFC's dynamic partnership in DNA synthesis
Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...
The discovery of catalytic RNA transformed our understanding of life's beginnings. Clare Sansom explores how the RNA world ...
Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...
A research team has identified a new mechanism that controls DNA’s ability to replicate—and thereby a cell’s ability to ...
Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...
For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...
Cell division is a fundamental process that allows cells to replicate accurately and maintain tissue homeostasis. This ...
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