The 49ers expect tight end George Kittle to practice Wednesday and cornerback Charvarius Ward has returned to the team and will be evaluated in hopes of returning in Week 12 to face the Buffalo Bills.

The AFC had a major shake-up after the thrilling Week 11 slate, even if not much changed in the standings. The Kansas City ...

Meanwhile, Harbaugh is in Los Angeles, coaching the Chargers to a 7-3 record, with quarterback Justin Herbert looking like a superstar. And the reigning college national champion is bringing the quirk ...

One of the best pass-catchers in the NFL will be on show when Trey McBride and the Arizona Cardinals visit the Seattle ...

The injury-prone San Francisco 49ers are monitoring yet another health issue, this one involving quarterback Brock Purdy's ...

Who will win the NFC North? NFL division standings, odds, schedule for Detroit Lions, Minnesota Vikings, Green Bay Packers, ...

Brock Purdy injury update. The 49ers added Purdy to the injury report on Monday, listing their starting quarterback with ...

What are the lines we're looking at before movement later in the week? Here are some early picks for Week 12 of the NFL and ...

The San Francisco 49ers got a taste of what their defense looks like without Nick Bosa in the second half of a loss to Seattle.

Having spent his first three NFL seasons residing in the NFC West with the Rams, like the Seahawks, who had lost six straight ...

As the San Francisco 49ers returned to the field against the Seattle Seahawks on Sunday, George Kittle 's wife, Claire Kittle ...

NFL officials have once again screwed over the 49ers with a pivotal blown call in a game against the Seahawks. On their second-to-last possession of the game, the Niners were stopped on the Seattle 42 ...