Correspondence to Michel de Lorgeril PRETA – TIMC – IMAG, Equipe Coeur & Nutrition, Faculté de Médecine, Domaine de la Merci, Université de Grenoble, 38706 La Tronche, France; michel.delorgeril{at}ujf ...

Objectives Systematic reviews and meta-analyses are the foundation of modern evidence-based medicine and their use is becoming more prolific than randomised trials. However, systematic reviews are ...

Evidence-informed decision-making (EIDM) refers to the systematic and transparent process of identifying, appraising and mobilising the best available evidence to inform the development of safe and ...

Objectives Cancer overdiagnosis is a polarizing topic, with much disagreement on its drivers, magnitude, and implications. Overdiagnosis is also complex, as various factors interact to influence said ...

As a heart surgeon, you regularly perform aortic valve replacement, using a median sternotomy technique. However, you are aware that less-invasive options are available, and you wonder whether these ...

Correspondence to Dr Igho J Onakpoya, Nuffield Department of Primary Care Health Sciences, University of Oxford, Centre for Evidence-Based Medicine, Oxford OX2 6GG, UK; igho.onakpoya{at}phc.ox.ac.uk ...

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...

Objective To estimate associations between trivalent influenza vaccination and COVID-19 mortality as well as severe clinical outcomes among hospitalised patients. Design Retrospective observational ...

2 Center for Evidence-based Medicine & Health Outcome Research, University of South Florida & H Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA ...

Objectives Bronchiolitis is the commonest reason for hospital admission in infants in the first year of life. 1 Bronchiolitis, a viral chest infection, is a clinical diagnosis with no effective ...

Introduction There is growing interest in applying shared decision making approaches to support informed consent, a vital but challenging aspect of conducting clinical research. We systematically ...

1 Kuopio Research Centre of Geriatric Care and Unit of Clinical Pharmacology and Geriatric Pharmacotherapy, School of Pharmacy, University of Eastern Finland, kuopio Campus, Yliopistonranta 1, P.O.