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The efficiencies with which activated B lymphocytes proliferate and develop into antibody (Ab)- secreting plasma cells are critical determinants of adaptive humoral immunity and central to sustaining ...
Optimised genome editing for precise DNA insertion and substitution using Prime Editors in zebrafish
This study presents a valuable comparison of the efficiency and precision of two prime editing methods to introduce single-nucleotide variants and longer exogenous DNA sequences into the zebrafish ...
The study presents valuable theoretical insights by attempting to classify pattern-forming gene subnetworks and exploring their potential mechanisms. However, the results are incomplete, as they rely ...
The study provides valuable technical advances to generate and isolate neural rosettes. The technique is robust, as indicated by both reviewers. The evidence is solid, as shown in orthogonal ...
Time-resolved fluorescence resonance energy transfer reveals conformational energetics of a bacterial cyclic nucleotide-gated ion channel.
This important study reports an advancement in the diagnosis of Animal African Trypanosomosis (AAT), which adapts a CRISPR-based diagnostic tool (SHERLOCK4AAT) to detect different trypanosome species ...
Reviewer #1 (Public review): Summary: The authors developed SHERLOCK4AAT, a CRISPR-Cas13a-based diagnostic toolbox for detecting multiple trypanosome species responsible for animal African ...
Reviewer #2 (Public review): The chemoreceptor proteins expressed by olfactory sensory neuron differ in their selectivity such that glomeruli vary in the breadth of volatile chemicals to which they ...
Altmetric provides a collated score for online attention across various platforms and media. See more details Flat clathrin lattices accumulate in cells depleted of CCDC32. (A-B) Representative PREM ...
Targeting CD81+ fibroblasts–neutrophils axis provides a new strategy for periodontitis treatment.
Immunology and Inflammation Xcr1 + type 1 conventional dendritic cells are essential mediators for atherosclerosis progression ...
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