SCOTT CITY, Mo. (KFVS) - Multiple crews are on the scene of a house fire in Scott City on Tuesday morning, October 1.

RIPLEY COUNTY, Mo. (KFVS) - A Naylor, Missouri woman was seriously injured in a single-vehicle crash on Monday, September 30.

We’re on Week 6 of Heartland Football Friday Top 12 Plays. Take a look at some of the best plays we saw this past Friday.

Contour Airlines begins air service from Cape Girardeau Regional Airport to Chicago O'Hare International Airport on Tuesday, Oct. 1.

There are 448 “missing person” cases in the state of Missouri right now, and nearly 25,000 nationwide, according to the ...

SIU Public Health is working with the Carbondale Community High School Key Club and SIU Eta Sigma Gamma to host the ninth ...

Law enforcement is searching for a Paducah man who is wanted in connection with a drug trafficking investigation.

(TMX) - John Deere is recalling more than 164,000 Compact Utility Tractors across the U.S. and Canada because they can lose ...

Dockworkers at ports from Maine to Texas have started walking picket lines in a strike over wages and automation that could reignite inflation and cause shortages of goods if it goes on more than a ...

Karolina tragically lost her life when her family’s home caught fire on September 8. Now, her mother is sharing her story and ...

Three people were arrested over the past week in western Kentucky, all in connection with a drug investigation.

WALTONVILLE, Ill. (KFVS) - Two men were arrested after a report of shots fired in Waltonville. Christopher M. Redman, 58, was ...