Transthyretin amyloidosis (ATTR-CM) occurs when your liver produces faulty transthyretin (TTR) proteins. Clumps of these abnormal proteins (called fibrils) build up in your heart’s main …

Transthyretin amyloidosis is a slowly progressive condition characterized by the buildup of abnormal deposits of a protein called amyloid (amyloidosis) in the body's organs and tissues. …

ATTRm amyloidosis is a multi-system disorder with cardiovascular, peripheral and autonomic nerve involvement that can be difficult to diagnose due to phenotypic heterogeneity.

Jul 15, 2025 · ATTR amyloidosis results from the misfolding of transthyretin (TTR), a protein responsible for transporting thyroid hormone and vitamin A. It can occur in a hereditary …

Hereditary ATTR amyloidosis is caused by a change or mutation in the transthyretin (TTR) gene which is inherited (i.e. runs in families). This change makes the TTR protein unstable so it …

We deliver exceptional care for transthyretin (TTR) amyloidosis, also referred to as familial amyloidosis because it can run in families. We offer the full range of amyloidosis care options, …

Mutated transthyretin is associated with the formation of amyloid fibrils, leading to the development of TTR-related amyloidosis (ATTR). These fibril proteins are deposited into …

Chronic inflammatory conditions such as rheumatoid arthritis or chronic infections such as bronchiectasis are associated with chronically elevated levels of the inflammatory protein, …

Stewart M, Loftus J, Lenderking WR, et al. Characterizing disease burden in an ultra-rare disease in the United States: transthyretin (TTR) amyloidosis patients & caregivers.

Nov 13, 2024 · ATTR amyloidosis is related to the abnormal production and buildup of a type of amyloid called transthyretin. Learn about symptoms, diagnosis, and treatments.