What is chromosome translocation? A rearrangement of chromosomes doesn't tend to affect health if it's balanced. They are pretty common because of this. However they can make it more difficult to pass on the correct amount of genetic information and this can cause problems with pregnancy, miscarriage and babies born with other problems. Some people see a Genetic counsellor once a translocation has been identified to help them understand it and what risks there are to them and their family. #gene